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Enjoy a taste of Aloha with these beautiful Fine Art Prints by Pacifica Island Art - printed in Maui, Hawaii. This print will look wonderful framed in the home, office or restaurant and is perfect for the Vintage Art Collector. - ABOUT THE ARTIST - Kerne Erickson - For over 30 years, award-winning artist Kerne Erickson’s retro-style travel posters have been taking viewers ‘on location’ to popular destinations around the globe. Inspired by vintage vacation photos, brochures and other graphics, his depictions are painstakingly researched and meticulously depicted for historical accuracy as well as irresistible nostalgia. At a time when sterile, computer-generated art has become popular, it’s refreshing to see an artist like Kerne who can work his way from a well composed pencil drawing, through transparent layers of under painting, building depth and tonality until finally adding the finishing touches that bring the work into focus. His work is a perfect blend of traditional technique and modern painting mediums. Erickson, a graduate of Los Angeles Art Center College, worked for years as a freelance graphic artist on client commissions which served to develop his distinctive style. He is now a freelance artist working at his home in Orange County, California where he lives with his family.
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;